News & Publications

• 1978 –Discovery of Qa-1–restricted CD8⁺ Tregs.

  Identification of a Subpopulation of T-Helper Cells that Induces Feedback Inhibition | JJ Exp Med, 1978 | Dr. Harvey Cantor

• 2011 – Identification of Ly49 as key marker for Qa-1–restricted CD8⁺ Tregs.

  CD8⁺ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice | PNAS, 2011 | Dr. Harvey Cantor

• 2016 – Discovery of tissue-specific Qa-1–restricted CD8⁺ Tregs.

  Targeting Non-classical Myelin Epitopes to Treat Experimental Autoimmune Encephalomyelitis | Scientific Reports (Nature portfolio), 2016 | Dr. Xiaolei Tang

• 2022 – Identification of KIR as marker for human HLA-E–restricted CD8⁺ Tregs.

  KIR⁺ CD8⁺ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 | Science, 2022 | Dr. Mark Davis

Publications

TangGene is advancing TG-MS01 toward IND-enabling studies. Updates on milestones, collaborations, and achievements will be published here.

Company Updates (Placeholder)

Stay Connected

For press inquiries, media collaborations, or investor questions, we welcome you to connect with us. TangGene is building the future of autoimmune care, and we invite you to be part of our journey.