News & Publications

DECEMBER 6, 2025

TangGene Scientific Co-Founders Publish Invited Review in Annual Review of Immunology.

News

Official announcements, press releases, and key corporate and scientific milestones

JANUARY 5, 2026

TangGene Appoints Former GSK Senior Executive Dr. Catherine Sohn as Senior Strategic Advisor.

• 1978 –Discovery of Qa-1–restricted CD8⁺ Tregs.

  Identification of a Subpopulation of T-Helper Cells that Induces Feedback Inhibition | JJ Exp Med, 1978 | Dr. Harvey Cantor

• 2011 – Identification of Ly49 as key marker for Qa-1–restricted CD8⁺ Tregs.

  CD8⁺ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice | PNAS, 2011 | Dr. Harvey Cantor

• 2016 – Discovery of tissue-specific Qa-1–restricted CD8⁺ Tregs.

  Targeting Non-classical Myelin Epitopes to Treat Experimental Autoimmune Encephalomyelitis | Scientific Reports (Nature portfolio), 2016 | Dr. Xiaolei Tang

• 2022 – Identification of KIR as marker for human HLA-E–restricted CD8⁺ Tregs.

  KIR⁺ CD8⁺ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 | Science, 2022 | Dr. Mark Davis

• 2025 – Field-defining synthesis of CD8⁺ regulatory T cells and in vivo immune tolerance.

  CD8⁺ Regulatory T Cells | Annual Review of Immunology, 2025 | Dr. Harvey Cantor & Dr. Xiaolei Tang

Publications

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